Performance visualizations using XML representations

The intermediate representation (IR)forms the information exchanged among different passes of program compilation. The intermediate format proposed for extensibility and persistence is written in XML. In this way, the program transformations that were internal to the compiler become visible. The hierarchical structure of XML makes a natural representation for the abstract syntax tree (AST). A compiler can parse the program source into an IR, then output it as an XML document. Separated by orthogonal namespaces, other IRs are also presented in the same XML document, gathering program information such as dependence vectors, transforming matrices, iteration spaces dependence graphs and cache reuse distances. This XML document can be exchanged between the compiler and program visualizers for parallelism and locality

Adventitious shoot regeneration from in vitro stem explants of Phellodendron amurense

An efficient in vitro plant regeneration system from stem explants was established in Phellodendron amurense. Factors influencing shoot regeneration from stems including culture medium type, combinations of plant growth regulators and carbon source in the medium were investigated. Adventitious shoot regeneration was significantly influenced by the type of medium. Murashige and Skoog medium (MS) was the best for promoting shoot regeneration, followed by Gamborg medium (B5) and woody plant medium (WPM). The combination of 6-benzyladenine (BA) and naphthaleneacetic acid (NAA) produced better results for shoot regeneration. The optimum shoot regeneration frequency (74.5%) and number of shoots per explant (12.3) was achieved using MS medium supplemented with 29.7 M BA and 5.8 M NAA. High concentrations of BA and NAA in the medium inhibited shoot formation. Among the three sugars tested, 20 g dm-3 glucose was the optimum for shoot regeneration. Rooting of regenerated shoots was successful on 1/4-strength MS medium with the addition of 15.4 M IBA. Almost 100% plantlets survived acclimatization after transferred to soil.Key words: Phellodendron amurense, callus, shoot regeneration, stem explants

Gate controlled electronic transport in monolayer MoS2 field effect transistor

published_or_final_versio

Links of cytoskeletal integrity with disease and aging

Aging is a complex feature and involves loss of multiple functions and nonreversible phenotypes. However, several studies suggest it is possible to protect against aging and promote rejuvenation. Aging is associated with many factors, such as telomere shortening, DNA damage, mitochondrial dysfunction, and loss of homeostasis. The integrity of the cytoskeleton is associated with several cellular functions, such as migration, proliferation, degeneration, and mitochondrial bioenergy production, and chronic disorders, including neuronal degeneration and premature aging. Cytoskeletal integrity is closely related with several functional activities of cells, such as aging, proliferation, degeneration, and mitochondrial bioenergy production. Therefore, regulation of cytoskeletal integrity may be useful to elicit antiaging effects and to treat degenerative diseases, such as dementia. The actin cytoskeleton is dynamic because its assembly and disassembly change depending on the cellular status. Aged cells exhibit loss of cytoskeletal stability and decline in functional activities linked to longevity. Several studies reported that improvement of cytoskeletal stability can recover functional activities. In particular, microtubule stabilizers can be used to treat dementia. Furthermore, studies of the quality of aged oocytes and embryos revealed a relationship between cytoskeletal integrity and mitochondrial activity. This review summarizes the links of cytoskeletal properties with aging and degenerative diseases and how cytoskeletal integrity can be modulated to elicit antiaging and therapeutic effects

Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Aberrant DNA methylation plays a pivotal role in carcinogenesis and its mapping is likely to provide biomarkers for improved diagnostic and risk assessment in prostate cancer (PCa). We quantified and compared absolute methylation levels among 28 candidate genes in 48 PCa and 29 benign prostate hyperplasia (BPH) samples using the pyrosequencing (PSQ) method to identify genes with diagnostic and prognostic potential. RARB, HIN1, BCL2, GSTP1, CCND2, EGFR5, APC, RASSF1A, MDR1, NKX2-5, CDH13, DPYS, PTGS2, EDNRB, MAL, PDLIM4, HLAa, ESR1 and TIG1 were highly methylated in PCa compared to BPH (p < 0.001), while SERPINB5, CDH1, TWIST1, DAPK1, THRB, MCAM, SLIT2, CDKN2a and SFN were not. RARB methylation above 21% completely distinguished PCa from BPH. Separation based on methylation level of SFN, SLIT2 and SERPINB5 distinguished low and high Gleason score cancers, e.g. SFN and SERPINB5 together correctly classified 81% and 77% of high and low Gleason score cancers respectively. Several genes including CDH1 previously reported as methylation markers in PCa were not confirmed in our study. Increasing age was positively associated with gene methylation (p < 0.0001). Accurate quantitative measurement of gene methylation in PCa appears promising and further validation of genes like RARB, HIN1, BCL2, APC and GSTP1 is warranted for diagnostic potential and SFN, SLIT2 and SERPINB5 for prognostic potential

Antioxidant, antibacterial and α-glucosidase inhibitory activities of different extracts of Cortex Moutan

Different extracts of Cortex Moutan (CM) were investigated for their antioxidant, antibacterial and α- glucosidase inhibitory activities. The content of paeonol was quantified by high performance liquid chromatography (HPLC). The results show that the yield of acetone extract (57.14%) was significantly higher than those of other solvents. The ethyl-acetate extract exhibited maximum paeonol concentration (60.69 μg/ml), good antibacterial activities (MIC = 100 μg/ml) against Escherichia coli and possessed significant α-glucosidase inhibitory activity. In addition, among all of the extracts, ethylacetate extract demonstrated a high total phenolic value of 127.12 ± 1.42 mg GAE/g, high DPPH radical scavenging activity with an IC50 of 19.88 ± 0.26 μg/ml, and significant reducing power, suggesting that CM is a potential source of natural antioxidants.Key words: Cortex Moutan, antioxidant, 11-diphenyl-2-picrylhydrazyl hydrate (DPPH), reducing power, antibacterial, α-glucosidas

Quantum fluctuations in high field magnetization of 2D square lattice J1-J2 antiferromagnets

The J1-J2 square lattice Heisenberg model with spin S=1/2 has three phases with long-range magnetic order and two unconventionally ordered phases depending on the ratio of exchange constants. It describes a number of recently found layered vanadium oxide compounds. A simple means of investigating the ground state is the study of the magnetization curve and high-field susceptibility. We discuss these quantities by using the spin-wave theory and the exact diagonalization in the whole J1-J2 plane. We compare both results and find good overall agreement in the sectors of the phase diagram with magnetic order. Close to the disordered regions the magnetization curve shows strong deviations from the classical linear behaviour caused by large quantum fluctuations and spin-wave approximation breaks down. On the FM side (J1<0) where one approaches the quantum gapless spin nematic ground state this region is surprisingly large. We find that inclusion of second order spin-wave corrections does not lead to fundamental improvement. Quantum corrections to the tilting angle of the ordered moments are also calculated. They may have both signs, contrary to the always negative first order quantum corrections to the magnetization. Finally we investigate the effect of the interlayer coupling and find that the quasi-2D picture remains valid up to |J_\perp/J1| ~ 0.3.Comment: 13 pages, 6figure

铁调素(Hepcidin)在骨质矿化中的作用

2005-2006 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Attack and Defence of Ethereum Remote APIs

© 2018 IEEE. Ethereum, as the first Turing-complete blockchain platform, provides various application program interfaces for developers. Although blockchain has highly improved security, faulty configuration and usage can result in serious vulnerabilities. In this paper, we focus on the security vulnerabilities of the official Go-version Ethereum client (geth). The vulnerabilities are because of the insecure API design and the specific Ethereum wallet mechanism. We demonstrate attacks exploiting these vulnerabilities in an Ethereum testbed. The vulnerabilities are confirmed by the scanning results on the public Internet. Finally, corresponding countermeasures against attacks are provided to enhance the security of the Ethereum platform